J.A. Gavira

Protein Crystallization & Crystallography

UGR CSIC LEC CSIC-UGR

Old News


ActaD Special Issue on Neutron scattering

Silica-gel


Seeding from silica-reinforced lysozyme crystals for neutron crystallography

Acta Cryst. D74, (2018) 1200-7. Gavira, J.A., Conejero-Muriel, M. and Delgado-López, J.M.,
doi: 10.1107/S2059798318016054

HYDROgels

Peptide hydrogel


Article »

Protein crystallization in short-peptide supramolecular hydrogels: a versatile strategy towards biotechnological composite materials
CrystEngComm, (2015) 17, 8072-78. Conejero-Muriel, Mayte, Contreras-Montoya, Rafael, Díaz-Mochón, Juan J., Álvarez de Cienfuegos, Luis and Gavira, José A.
doi: 10.1039/c5ce00850f

IDEAL: "Patentan un nuevo hidrogel que abre las puertas al desarrollo de fármacos más efectivos...." More »

Peptide hydrogel


Article »

Influence of the chirality of short peptide supramolecular hydrogels in protein crystallogenesis
Chem Commun, (2015) 51, 3862-65. Conejero-Muriel, M., Gavira, J. A., Pineda-Molina, E., Belsom, A., Bradley, M., Moral, M., Duran, J. D., Luque Gonzalez, A., Diaz-Mochon, J. J., Contreras-Montoya, R., Martinez-Peragon, A., Cuerva, J. M. and Alvarez de Cienfuegos, L. doi: 10.1039/c4cc09024a

Other sources

UGR »

AulaMagna »

SoloCiencia »

Miradaprofesional »


ASTROBIOLOGY

Back from the Dead: Scientists "Resurrect" Ancient Proteins to Learn about Primordial Life on Earth. Geological evidence tells us that ancient Earth probably looked and felt very different from the planet we all recognize today. Billions of years ago, our world was a comparatively harsh place.... More »

Ancestral Tactamase


Article »

Phenotypic comparisons of consensus variants versus laboratory resurrections of Precambrian proteins
Proteins, (2014) 82, 887-96. Risso, V. A., Gavira, J. A., Gaucher, E. A. and Sanchez-Ruiz, J. M. doi: 10.1002/prot.24575


IYCr crystallization series


Introduction to protein crystallization

A. McPherson and J. A. Gavira

Synopsis: The gateway to X-ray crystallography is the growth of macromolecular crystals. An attempt is made here to acquaint investigators with the principles and practice of protein crystallization, some recent innovations, and to touch upon some of the remaining problems.

Article »



Conservation of Protein Structure over Four Billion Years.
Structure, (2013) 21, (9), 1690-1697. Ingles-Prieto, A.; Ibarra-Molero, B.; Delgado-Delgado, A.; Perez-Jimenez, R.; Fernandez, J. M.; Gaucher, E. A.; Sanchez-Ruiz, J. M.; Gavira, J. A. doi: 10.1016/j.str.2013.06.020


ACS News: Resurrection of 3-billion-year-old antibiotic-resistance proteins

Scientists are reporting "laboratory resurrections" of several 2-3-billion-year-old proteins that are ancient ancestors of the enzymes that enable today's antibiotic-resistant bacteria to shrug off huge doses of penicillins, cephalosporins and other modern drugs..... More »

Other sources

Worldpress »


Alactamase

Article »

Hyperstability and Substrate Promiscuity in Laboratory Resurrections of Precambrian b-Lactamases.
J Am Chem Soc, (2013) 135, (8), 2899-902. Risso, V. A.; Gavira, J. A.; Mejia-Carmona, D. F.; Gaucher, E. A.; Sanchez-Ruiz, J. M. doi: 10.1021/ja311630a


BBC: Resurrected protein's clue to origins of life

New reconstructions of ancient proteins have provided clues to the habitat and origins of life on Earth. The resurrected protein is thought to have existed almost four billion years ago in single-celled organisms linked to the earliest ancestor of all life..... More »

Other sources

AAAS Eurekalert » Livescience » SINC » El Mundo »

Ancestral Thioredoxins


Article »

ESRF Scientists "resurrect" ancient proteins to provide clues about molecular innovation

A growing body of research on the use of ancestral protein resurrection has been published in recent years to address a variety of issues on protein evolution and protein engineering. In a study published in Nature Communications, an International team of scientists has demonstrated the high potential of this evolutionary approach to endow new activities into ancient enzymes...... More »

Other sources

Scicasts » Science Newsline » GEN » Phys.org » EurekAlert! »


Article »

ABB Special Issue

Peptide hydrogel


Macromolecular crystallography: An old science with new perspectives
ABB, (2016) 602, 1-2. Cámara-Artigas, A. & Gavira, J.A.
doi: 10.1016/j.abb.2016.05.004

ISBC2019

International School on Biological Crystallization

ISBC2019

ESCG2 (ECCG6)

Second European School on Crystal Growth

ESCG2
Varna, 13-16 September

ECM31

31st European Crystallographic Meeting

ecm31

ISC2018

International School of Crystallization

ISC2017

AMMC VIII

Advanced Methods in Macromolecular Crystallization VII

AMMC-VIII

ISBC2017

International School of Crystallization

ISC2017

ICCBM16

16th International Conference on the Crystallization of Biological Macromolecules

ICCBM16

ISC2016

International School of Crystallization

ISC2016

ISBC2015

International School of Crystallization

ISBC2015

ICCBM15

15th International Conference on the Crystallization of Biological Macromolecules

ICCBM15

ISC2014

International School of Crystallization

ISC2014

ISBC2013

International School on Biological Crystallization

ISC2014